离子色谱在乙醇压力作用下对运动发酵单胞菌的转录组进行剖析
transcriptome profiling of zymomonas mobilis under ethanol stress
离子色谱在乙醇压力作用下对运动发酵单胞菌的转录组进行剖析
abstract
background: high tolerance to ethanol is a desirable characteristics for ethanologenic strains used in industrial ethanol fermentation. a deeper understanding of the molecular mechanisms underlying ethanologenic strains tolerance of ethanol stress may guide the design of rational strategies to increase process performance in industrial alcoholic production. many extensive studies have been performed in saccharomyces cerevisiae and escherichia coli.
however, the physiological basis and genetic mechanisms involved in ethanol tolerance for zymomonas mobilis are poorly understood on genomic level. to identify the genes required for tolerance to ethanol, microarray technology was used to investigate the transcriptome profiling of the ethanologenic z. mobilis in response to ethanol stress.
results: we successfully identified 127 genes which were differentially expressed in response to ethanol. ethanol up- or down-regulated genes related to cell wall/membrane biogenesis, metabolism, and transcription. these genes were classified as being involved in a wide range of cellular processes including carbohydrate metabolism, cell wall/ membrane biogenesis, respiratory chain, terpenoid biosynthesis, dna replication, dna recombination, dna repair,
transport, transcriptional regulation, some universal stress response, etc.
conclusion: in this study, genome-wide transcriptional responses to ethanol were investigated for the first time in z. mobilis using microarray analysis.our results revealed that ethanol had effects on multiple aspects of cellular metabolism at the transcriptional level and that membrane might play important roles in response to ethanol. although the molecular mechanism involved in tolerance and adaptation of ethanologenic strains to ethanol is still
unclear, this research has provided insights into molecular response to ethanol in z. mobilis. these data will also be helpful to construct more ethanol resistant strains for cellulosic ethanol production in the future.
shopees怎么设置货到付款
国际台湾转运仓 台湾转运仓到大陆
模具煅烧马弗炉
大型平面磨床的优势
藻华的定义-湖泊、海洋上的藻类繁殖多了好还是不好
离子色谱在乙醇压力作用下对运动发酵单胞菌的转录组进行剖析
恒温摇床与全温摇床的区别是什么？
预制发泡中会出现不良反应和保温管直埋铺设的优势
沃华远达地埋式一体化医疗污水处理设备
国际海运海上风险有哪些
微型直线导轨有什么特点和哪些使用优势？
GARBURG复卷机GEA 200 简介
污水紫外线消毒器所用的汞齐灯有哪些特征？
市场追踪丨2月仪器及检测行业市场动态（国内篇）
热导式流量开关基本介绍
1.4523钢材具体规格
研祥工业底板IPC-610
刺山茶根皮的功效与作用
电脑控制立式箱式电炉
液压自动升降柱防撞杆是什么？适合用于什么场合？
离子色谱在乙醇压力作用下对运动发酵单胞菌的转录组进行剖析
abstract
background: high tolerance to ethanol is a desirable characteristics for ethanologenic strains used in industrial ethanol fermentation. a deeper understanding of the molecular mechanisms underlying ethanologenic strains tolerance of ethanol stress may guide the design of rational strategies to increase process performance in industrial alcoholic production. many extensive studies have been performed in saccharomyces cerevisiae and escherichia coli.
however, the physiological basis and genetic mechanisms involved in ethanol tolerance for zymomonas mobilis are poorly understood on genomic level. to identify the genes required for tolerance to ethanol, microarray technology was used to investigate the transcriptome profiling of the ethanologenic z. mobilis in response to ethanol stress.
results: we successfully identified 127 genes which were differentially expressed in response to ethanol. ethanol up- or down-regulated genes related to cell wall/membrane biogenesis, metabolism, and transcription. these genes were classified as being involved in a wide range of cellular processes including carbohydrate metabolism, cell wall/ membrane biogenesis, respiratory chain, terpenoid biosynthesis, dna replication, dna recombination, dna repair,
transport, transcriptional regulation, some universal stress response, etc.
conclusion: in this study, genome-wide transcriptional responses to ethanol were investigated for the first time in z. mobilis using microarray analysis.our results revealed that ethanol had effects on multiple aspects of cellular metabolism at the transcriptional level and that membrane might play important roles in response to ethanol. although the molecular mechanism involved in tolerance and adaptation of ethanologenic strains to ethanol is still
unclear, this research has provided insights into molecular response to ethanol in z. mobilis. these data will also be helpful to construct more ethanol resistant strains for cellulosic ethanol production in the future.
shopees怎么设置货到付款
国际台湾转运仓 台湾转运仓到大陆
模具煅烧马弗炉
大型平面磨床的优势
藻华的定义-湖泊、海洋上的藻类繁殖多了好还是不好
离子色谱在乙醇压力作用下对运动发酵单胞菌的转录组进行剖析
恒温摇床与全温摇床的区别是什么？
预制发泡中会出现不良反应和保温管直埋铺设的优势
沃华远达地埋式一体化医疗污水处理设备
国际海运海上风险有哪些
微型直线导轨有什么特点和哪些使用优势？
GARBURG复卷机GEA 200 简介
污水紫外线消毒器所用的汞齐灯有哪些特征？
市场追踪丨2月仪器及检测行业市场动态（国内篇）
热导式流量开关基本介绍
1.4523钢材具体规格
研祥工业底板IPC-610
刺山茶根皮的功效与作用
电脑控制立式箱式电炉
液压自动升降柱防撞杆是什么？适合用于什么场合？